Capsugel to Highlight Innovative Capsule Technologies and Dosage Type Solutions at the 2014 AAPS Annual Meeting and Exposition

(PRWEB) October 23, 2014

Capsugel scientists will talk about a range of advancements – like bioavailability enhancement and multi-particulate technologies, dry powder inhalation (DPI) technologies, and alternate-polymer and other specialized capsule technologies – at the 2014 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, which runs November 2-six in San Diego, Calif. The business will also showcase specialized gear to help crucial technologies in encapsulation and bioreactor method handle.

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“It is an exciting time to be a scientist at Capsugel. Our advanced science and engineering, expanded technologies offerings, and the increasing synergies in between our Hard Capsule and Dosage Form Options (DFS) company units are top to new possibilities to develop value for our clients,” stated Keith Hutchison, Ph.D., Senior Vice President, Analysis &amp Improvement, Capsugel. “At AAPS, we look forward to discussing our approach to addressing customers’ most-pressing formulation challenges, including low and variable drug absorption, high-potency/low-dose specifications and modified drug release profiles and to demonstrating our distinctive ability to style, create and manufacture both state-of-the-art capsules and completed dosage forms.”

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Firm scientists will present 20 technical posters and host a series of seminars on important innovations. Highlights consist of: &#13

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New lipid multi-particulate (LMP) technologies, primarily based on Capsugel’s proprietary melt-spray congeal processing, supplying the functionality of lipid-based formulations with the patient and consumer rewards related with a multi-particulate drug delivery&#13
Coni-Snap® sprinkle capsules developed for populations with swallowing difficulties, providing reproducible ease of opening for sufferers and caregivers&#13
Integrated formulation and specialized capsule providing for Inhalation items, like particle engineering for optimized formulations and specialized DPI capsules for pulmonary delivery&#13
Advancements in spray-dried dispersion and other bioavailability-enhancement technologies, pioneered by Bend Investigation, now a division of Capsugel Dosage Form Solutions.

Specialized equipment that will be featured at the booth involves Capsugel’s new Modular Automated Sampling Technology™ platform, or MAST, and its Xcelodose® precision powder micro-dosing technique. MAST is an automated, aseptic bioreactor sampling method that will aid advance the bioprocess sector toward actual-time testing, predictive control and general bioprocess guidance. Capsugel’s Xcelodose® system shortens drug improvement time, speeds 1st-in-human trials and lowers charges by minimizing the want for formulation and stability research just before API proof of notion is established.

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Pay a visit to Capsugel’s booth #1422 to learn about innovative dosage technology and manufacturing options for the pharmaceutical business. An overview of poster presentations and seminars can be identified right here. Schedule a meeting with Capsugel in advance right here, and follow updates about the meeting at http://www.capsugel.com.

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ABOUT CAPSUGEL&#13

Capsugel is a international leader in delivering high-quality, revolutionary dosage types and solutions to its clients in the overall health care industry. The company’s Difficult Capsule organization offers clients the broadest portfolio of gelatin, vegetarian, and other specialized capsule technologies. Capsugel’s Dosage Form Solutions (DFS) organization utilizes an array of proprietary technologies and specialized manufacturing capabilities to resolve customers’ most pressing item improvement challenges, which includes bioavailability enhancement, modified release, abuse deterrence, biotherapeutic processing, and inhalation formulation. The company’s fast-to-clinic program streamlines solution development from pre-formulation via clinical and commercial provide for completed dosage types. Headquartered in Morristown, N.J., Capsugel serves a lot more than 4,000 clients in a lot more than one hundred nations. For extra information, go to http://www.capsugel.com.

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For media inquiries, please make contact with Christina Chnaider at Christina(dot)Chnaider(at)capsugel(dot)com.

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Precision Turned Components: Meeting varying specifications of Industries

Precision Turned Components: Meeting varying specifications of Industries

Issues are shaped and turned, this is completed so that very best out of them can be extracted. Tree’s planks are cut and shaped into log which are further used to craft furnishings. Similarly components are to be shaped for tapping maximum out of them.

Metal turning is procedure in which this material’s outer surface is removed. Precision turned elements are ready by rotating workpiece. Turning is utilized for decreasing the diameter of the workpiece. Precision components’ surfaces are placed parallel to the cutting tool. This can be completed manually, with use of lathe which is carried out continuous supervision of operator.  CNC turned components are fabricated employing computerized machines which is termed as CNC.

Precision turned parts are obtained when they are rotated and the cutting tool is traversed along 2 axes of motion to fabricate with precise diameters and depths.  Precision turned elements can either be get right after turning them inside or outdoors the cylinder. If turned inside the cylinder than the precision components are of a variety of geometries. CNC turned components are getting obtained from the machines from last three quarters of twentieth century.

Turning activity is usually carried out on a lathe, which is regarded to be the oldest machine tools. It is essentially of 4 distinct varieties such as taper turning, profiling, straight turning or external grooving. Precision turned elements produced are in a variety of shapes of supplies like curved,  straight, conical or grooved workpiece. Turning make use of easy single-point cutting tools. Optimum set of tools angles are there with each and every set of workpieces which came into getting more than the  years. Chips are bits of waste metal which are left after turning operations.

Metal turning is the most basic machining processes. In this operation, the element is rotated although single point cutting tool is actioned parallel to the axis of the rotation. This approach can be performed on the external surface or on the internal surface. The material which is worked upon is generally obtained following the approach of casting, drawing, forging and extrusion.

To generate a variety of precision elements like nuts, screws, bolts and so forth skilled labor is required and production is carried on in slow procedure. The strategy is designing the components which are utilized in many applications.

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West Bromwich Spring Company Limited, George Street, West Bromwich – sign – Helical Operates

Image by ell brown
On George Street in West Bromwich is the West Bromwich Spring Co. Ltd.

It is also the Helical Functions.

The West Bromwich Spring has been the forefront of precision manufacturing given that 1896. We have maintained our position with a mixture of expertise based on technical encounter &amp continual approach development.

West Bromwich Spring Ltd

An old painted on sign on the far left of Helical Operates.

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Ethis Healthtech Announces Partnership with IROC Science and EyeKor to Provide Turnkey Solution for Meeting New European Regulatory Demands for Post-market Outcomes Data

ZURICH, MADISON, WI, and NEW YORK (PRWEB) September 11, 2014

Three companies—one European, two American—have teamed up to allow European manufacturers of implantable ophthalmic devices to comply with anticipated regulatory demands for ongoing post-marketplace outcomes information.

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In 2015, manufacturers of implantable health-related devices sold on the European market will likely be essential to offer information on the security and efficacy of their products—both prior to and now soon after their devices achieve regulatory approval. This will call for careful post-market place clinical studies to create data and reports that meet European regulators’ precise specifications.

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To meet this need, a collaborative group has been formed amongst Zurich-primarily based IROC Science to Innovation AG, a major ophthalmic consulting service with specialized experience in ophthalmic clinical trials EyeKor, LLC, a firm of American clinical trial authorities that has created a cloud-primarily based application application, EXCELSIOR™, constructed specifically for supporting image data collection and management of ophthalmic clinical trials and Ethis HealthTech, LLC, an American business that serves firms in the fields of eyecare and digital healthcare by supplying marketplace-entry arranging and help, fundraising, and strategic communications.

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According to IROC’s Founder and CEO Michael Mrochen, PhD, “The burden that the proposed regulations will place on the makers of implantable devices is substantial, so it was important to generate an efficient way for organizations to receive post-marketplace outcomes information.”

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The outcome of the three-company collaboration is a turnkey resolution that provides European ophthalmic device producers a straightforward, expense-powerful way to meet the anticipated regulatory needs. This is produced possible by the joining of IROC’s in-depth understanding of the European regulatory landscape and experience in clinical trial design and operation with EyeKor’s unique clinical trial management software.

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EyeKor CEO Christopher J. Murphy, DVM, PhD, notes: “Excelsior™, EyeKor’s unique ophthalmic clinical trial software platform is developed to enhance speed and accuracy in the collection and interpretation of ophthalmological clinical trial data, creating it completely suited to the quickly-to-be-required phase IV clinical outcomes studies. It is particularly designed to enable efficient uploading and archiving of pictures collected utilizing diverse proprietary instrument software program to standardize the presentation format. Excelsior™ is a software platform that received FDA 510(k) clearance with distinct indications for use as a information management method for ophthalmic clinical trials.”

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As the person who engineered the collaboration, Luca Sergio, Managing Companion of Ethis HealthTech, notes: “We are pleased to join such a world-class team of recognized ophthalmic regulatory and clinical affairs experts and prime-notch ophthalmic imaging and reading center specialists to supply this robust, scalable, however easy-to-implement solution for our European business partners.”

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Discover more by going to booth A11 at the 2014 Annual Meeting of the European Society of Cataract &amp Refractive Surgeons, September 13-17, in London, or go to phaseiveyecarestudies.com.

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About IROC Science: IROC Science to Innovation AG provides consulting solutions for translational investigation projects in ophthalmology. The company’s multidisciplinary group has more than 15 years’ expertise in ophthalmic translational research projects and brings to the table in-depth knowledge with European regulatory bodies and the design and operation of clinical trials.

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About EyeKor: EyeKor, LLC, provides a complete spectrum of integrated ophthalmic clinical trial services with a network of established reading centers and clinical trial authorities. EyeKor’s proprietary application for supporting image data collection and management of ophthalmic clinical trials, EXCELSIOR™, enables image and data accessibility and progress tracking online any time, any location, as nicely as harmonization of image evaluation and grading in spite of differing instrumentation.

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About Ethis Healthtech, LLC: Ethis Healthtech serves firms in the fields of eyecare and mobile/digital healthcare by supplying industry-entry organizing and support, fundraising, and strategic communications. Ethis Healthtech supports all elements of its clients’ development activities.

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Media Inquiries: &#13

Luca Sergio&#13

+1-212-791-1440 (workplace)&#13

+1-201-744-3364 (mobile)&#13

lsergio(at)ethishealthtech(dot)com

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Southern Illinois Crankshafts Well Planned Growth Strategy Takes Another Step in Meeting the Growing Demands of the Oil and Gas Industry

Red Bud, Illinois (PRWEB) August 21, 2014

For the second time in four years, Southern Illinois Crankshaft (SIC) of Red Bud, Ill., is in a mode for growth and expanding the line of products they manufacture. Mike Ward, Commercial Lending Officer with National Bank, has worked with SIC owners Michael and Jeannie Schaefer since 2011 to help make financing a reality. SIC has become a precision manufacturer of crankshafts for oil and gas pumps and high-performance diesel engines.

The inception of the current expansion came as a customer request. During a recent forecast meeting with one of SIC larger customers, the purchasing manager at the company requested that SIC consider expanding their services to cover key parts used in high pressure hydraulic fracking operations. Because of SIC’s track record of meeting production times, producing a quality part, and keeping costs under control, the customer suggested expanding to meet their growing demands. National Bank took the time to understand the potential for SIC to be successful in these new areas and has enjoyed being a part of the Schaefer’s continued prosperity and job creation. Southern Illinois Crankshaft, Inc. will add 15,000 square feet to its current location. As part of the expansion, a new CNC horizontal boring and milling machine will handle product up to 22,000 pounds.

SIC was founded in 1985 by Michael and Jeannie Schaefer to manually machine crank shafts, for the agricultural, salvage, and heavy duty construction industries. The business started out in a 40’ X 40’ building in Evansville, Illinois. In 2005 SIC began manufacturing precision pump cranks and has developed strong relationships with the larger pump manufacturers. With the partnership of Mike Ward and National Bank, SIC has been able to plan out a multi stage growth plan that continues to this day. SIC is currently located in a 13,960 square foot facility with a state of the art line of CNC machining centers. “Our dedication to quality is without rival. We have delivered on our commitments 98% of the time in 2013,” said Michael Schaefer, president of SIC. Strict quality control has enabled SIC to achieve an unprecedented scrap rate of less than 1%. SIC has continued to grow by manufacturing pump crankshafts for the oil and gas industry.

National Bank is headquartered in Hillsboro, Illinois with 11 locations in South Central Illinois. The bank can be contacted from 8:30am to 4:30pm Monday through Friday and 8:30am to 12:00pm on Saturday at 800-717-3991.







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